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Laser Therapy in Healthcare

Advances in Diagnosis and Treatment

Edited by Rishabha Malviya, Dhanalekshmi Unnikrishnan Meenakshi and Priyanshi Goyal
Copyright: 2024   |   Status: Published
ISBN: 9781394237951  |  Hardcover  |  
286 pages
Price: $195 USD
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One Line Description
The book explores the intersection of laser technology and healthcare, highlighting its applications, challenges, and potential future in medical practice.

Audience
The book is intended for researchers, scientists, medical specialists, and industry engineers in various disciplines including biomedical sciences, biotechnology, microbiology, biochemistry, immunology, pharmacy and pharmaceutical sciences, bioinformatics, translational research, oncology, medical sciences.

Description
Implementing cutting-edge technologies has upended the paradigms of diagnosis and treatment in the ever-changing world of healthcare. Among these breakthroughs, the introduction of laser therapy stands out as a transformative moment, presenting a tremendous range of possibilities across a wide range of medical areas.
This book is the outcome of considerable research, combined experience, and a passionate study of lasers’ diverse uses in modern medicine. This thorough book navigates the complex field of laser physics, clinical applications, and novel treatment interventions that are transforming the healthcare sector.
This book acts as a roadmap through the various aspects of laser-based diagnostics and treatment modalities, from the basic chapters that explain the fundamentals of laser physics and its significant effects on tissues to the in-depth investigation of laser surgery in modern healthcare, including a variety of medical operations, such as brain surgery, cardiovascular procedures, dermatology, and oral surgery. Each chapter focuses on a different aspect of laser therapy, emphasizing its critical role in the treatment of many medical problems, from neurological disorders to oncology, dentistry, wound healing, and more. The book also includes an in-depth discussion of laser therapy’s classification, processes, clinical uses, and safety considerations.

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Author / Editor Details
Rishabha Malviya, PhD, is an associate professor in the Department of Pharmacy, School of Medical and Allied Sciences, Galgotias University. He has authored more than 150 research/review papers for national/international journals of repute. He has been granted more than 10 patents from different countries while a further 40 patents have either published or under evaluation. His areas of interest include formulation optimization, nanoformulations, targeted drug delivery, localized drug delivery, and characterization of natural polymers as pharmaceutical excipients.

Dhanalekshmi Unnikrishnan Meenakshi, PhD, holds a doctorate in Pharmacology from the Council of Scientific and Industrial Research (CSIR)- CLRI, India. She is a faculty member in the College of Pharmacy, National University of Science and Technology, Muscat, Sultanate of Oman. She has published extensively in nanomedicine, drug delivery, and formulation technology in peer-reviewed reputed journals and books and works on an array of projects relating to cancer and gene therapy, nanotechnology, and pharmacology.

Priyanshi Goyal is affiliated with the Department of Pharmacy at the School of Medical and Allied Sciences, Galgotias University, Greater Noida, Uttar Pradesh India where she gained her MPharm. She has authored two books and 3 book chapters. She has also published several research articles in various international journals.

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Table of Contents
Foreword
Preface
1. Leveraging the Concept of Laser Physics in Healthcare

1.1 Introduction
1.2 Physics of Laser
1.2.1 Principles of Optics
1.2.2 Laser Gadget
1.2.3 Laser Beam
1.2.3.1 Monochromatic
1.2.3.2 Coherent
1.2.3.3 Collimated
1.3 Laser Classification
1.4 The Workings of a Laser Therapy
1.5 Implications of Lasers on Tissues
1.5.1 Photothermal Impacts
1.5.2 Photochemical Effects
1.5.3 Photomechanical Effects
1.6 Spectroscopy Using a Laser-Induced Breakdown Mechanism: Its Use in Medicine and Other Fields
1.7 Applications of X-Ray and Computerized Tomography Technology in the Healthcare Industry
1.8 Conclusion
References
2. Laser Surgery in Contemporary Healthcare
2.1 Introduction
2.2 Applications of Laser Therapy in Different Treatments
2.2.1 Laser Lithotripsy
2.2.2 Brain Surgery
2.2.3 Epilepsy Surgery
2.2.4 Cardiovascular Surgery
2.2.5 Dermatology
2.2.6 Oncology
2.2.7 Oral Surgery and Dentistry
2.2.8 Cataract Surgery
2.2.9 Aesthetic and Reconstructive Surgery
2.2.10 Ablation of the Conductive Pathway
2.3 Conclusion
References
3. Management of Genitourinary Syndrome Associated with Dyspareunia with Laser Therapy
3.1 Introduction
3.2 Pathophysiology
3.3 Clinical Manifestation
3.3.1 Genital Symptoms
3.3.2 Sexual Symptoms
3.3.3 Urinary Symptoms
3.4 Laser Modalities and Mechanism on Tissue
3.5 Laser Therapy for Menopausal Genitourinary Syndrome
3.5.1 CO2 Laser
3.5.2 Erbium: Yttrium-Aluminum-Garnet
3.6 Adverse Effects and Complication
3.7 Safety of Laser Therapy
3.8 Conclusion
References
4. Early Detection of Cancer by Laser Therapy
4.1 Introduction
4.2 Photodynamic Therapy
4.2.1 Photosensitizer and Its Component
4.2.2 Mechanism of Photosensitizer
4.3 Laser Therapy Treatment
4.3.1 CO2
4.3.2 Argon
4.3.3 NAD: YAG
4.3.4 Low-Level Laser Treatment
4.3.5 Pulse Dye Laser
4.3.6 Potassium Titanyl Phosphate Laser
4.3.7 Intense Pulse Light
4.3.8 Flashlamp-Pumped Dye
4.4 Conclusion
References
5. Use of a Laser for Testing and Treating Sepsis
5.1 Introduction
5.2 Pathophysiology
5.3 Clinical Manifestation
5.3.1 Laboratory Method
5.3.1.1 Blood Culture
5.3.1.2 Cerebrospinal Fluid Culture
5.3.1.3 Urine Culture
5.3.1.4 Tracheal Aspartate Culture
5.3.1.5 Superficial Swab Cultures
5.3.1.6 Complete Blood Count Components and Peripheral Smear
5.3.1.7 C-Reactive Protein (CRP)
5.3.1.8 High Sensitivity-CRP (hs-CRP)
5.3.1.9 Procalcitonin (PCT)
5.3.1.10 Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass
Spectrometry (MALDI-TOF)
5.3.2 Molecular Method
5.3.1.1 Serum Amyloid A (SAA)
5.3.2.2 Lipopolysaccharide Binding Protein (LBP)
5.3.2.3 Cytokines and Chemokines
5.3.2.4 Interleukin- 6 (IL-6)
5.3.2.5 Interleukin-8 (IL-8)
5.3.2.6 Tumor Necrosis Factor Alpha (TNF- α)
5.3.2.7 Other Chemokines
5.4 Laser Treatment for Treating Sepsis
5.4.1 Laser Speckle Contrast Imaging
5.4.2 Laser Doppler Flowmetry
5.5 Conclusion
References
6. Laser Therapy to Treat Diabetic Macular Edema
6.1 Introduction
6.2 Pathophysiology
6.3 Clinical Characterization
6.3.1 Focal Macular Edema
6.3.2 Diffuse Macular Edema
6.3.3 Macular Ischemia
6.4 Diagnosis
6.5 Mechanism of Laser Therapy to Treat Diabetic Macular Edema
6.6 Laser Therapy for DME
6.6.1 Laser Photocoagulation
6.6.2 Using Lasers in Conjunction with Anti-VEGF Therapy
6.6.3 Navigated Laser Treatment
6.6.4 Subthreshold Micropulse Laser Therapy
6.6.5 Treatment for PDR Brought on by Using Pan-Retinal Photocoagulation
6.6.6 Selective Retinal Therapy
6.7 Clinical Lasers and Delivery Platforms: Upcoming Innovations
6.8 Conclusion
References
7. Diagnosis and Management of Sleep Bruxism Utilizing Laser Therapy
7.1 Introduction
7.2 Etiology
7.3 Pathophysiology
7.4 Diagnosis
7.5 Treatment of Sleep Bruxism
7.6 Case Study of Sleep Bruxism
7.7 Conclusion
References
8. Treatment for Osteoarthritis with Laser Technology
8.1 Introduction
8.2 Pathophysiology
8.3 Clinical Features
8.3.1 Knee Discomfort
8.3.2 Joint Stiffness
8.3.3 Growth and Swelling of the Bones
8.4 Risk Factors
8.5 Diagnosis
8.6 Laser Therapy for Osteoarthritis
8.7 Conclusion
References
9. Targeting Neurological Disorders with Laser Technology
9.1 Introduction
9.2 Symptoms of Brain Tumor
9.3 Diagnosis
9.3.1 Glial Tumor
9.3.1.1 Astrocytic Tumor
9.3.1.2 Cancers of the Oligodendroglia
9.4 Risk Factors
9.4.1 Ionizing Radiation
9.4.2 Radiofrequency Electromagnetic Radiation
9.4.3 Genetic Factors
9.4.4 N-Nitroso Compounds (NOCs)
9.5 Ablative Methods for Brain Surgery
9.5.1 Radiofrequency Thermal Ablation
9.5.2 Laser Interstitial Thermal Therapy
9.5.3 Stereotactic Radiosurgery
9.5.4 Thermal Ablation Using Concentrated Ultrasound
9.6 Brain Tumor
9.6.1 Radiofrequency/Microwaves
9.6.2 Laser Interstitial Thermotherapy
9.6.3 Ultrasound
9.6.4 Radiosurgery
9.7 Epilepsy Surgery
9.8 Conclusion
References
10. Diagnosis of Onychomycosis Using Laser Therapy
10.1 Introduction
10.2 Etiology and Epidemiology
10.3 Clinical Manifestation
10.4 Diagnostic Techniques
10.5 Complication
10.6 Treatment of Onychomycosis
10.6.1 Topical Antifungal Therapy
10.6.2 Laser Therapy
10.6.3 Photodynamic Therapy
10.6.4 Combination of Laser Therapy with Topical Antifungal Therapy
10.7 Prevention
10.8 Prognosis
10.9 Conclusion
References
11. Laser Treatment for Wound Healing
11.1 Introduction
11.2 Effect of Photon on Cell Level
11.3 Wound Healing Physiology
11.3.1 Physiology of Scar Formation
11.3.2 Pathology of Scar Formation
11.4 Treatment of Superficial Wounds with Laser Light
11.5 Low-Level Laser Therapy for Wound Healing
11.6 Laser Devices for Wound Healing
11.6.1 Laser Debridement
11.6.2 Fractional Photothermolysis
11.6.3 Photobiomodulation Therapy
11.6.4 Antimicrobial Blue Light
11.6.5 Photodynamic Therapy
11.6.6 Vascular Laser
11.7 Conclusion
References
12. Laser Therapy in Dentistry
12.1 Introduction
12.2 Classification of Laser in Dentistry
12.2.1 Hard Tissue Laser
12.2.2 Low-Level Lasers or Soft Tissue Lasers
12.3 Mechanism of Action of Laser
12.4 Laser–Tissue Interaction
12.4.1 Reflected
12.4.2 Absorbed
12.4.3 Transmitted
12.4.4 Scattered
12.5 Advantages and Disadvantages of Laser Therapy
12.6 Diagnosis
12.7 Clinical Applications
12.7.1 Cavity Preparation
12.7.2 Caries Removal
12.7.3 Restoration Removal
12.7.4 Etching
12.7.5 Gingiva and Periodontium
12.7.6 Pain
12.7.7 Oral Surgery
12.7.8 Premalignant and Malignant Lesions
12.8 Applications of Photodynamic Therapy
12.8.1 PDT in Oral Surgery
12.8.2 Dental Preventive Treatment
12.9 Laser Safety
12.10 Conclusion
References
13. Case Studies of Different Diseases Treated by Laser Therapy
13.1 Introduction
13.2 Case Studies of Cancer Diseases
13.3 Case Studies of Neurological Disorders
13.4 Conclusion
References
Index

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