Advances in Integrative Medicine introduces integrative medicine as a holistic approach to health that can effectively address the limitations and side effects of traditional allopathic treatments, providing valuable insights for practitioners and patients alike.
Table of ContentsPreface
Acknowledgment
About the Book
1. A General Introduction to Integrative Medicine (IM)Quazi Mohammad Imranul Haq, Ghulam Abbas and Mohd. Abdullah Al Sibani
1.1 Introduction
1.2 What is Integrative Medicine?
1.3 Philosophy of Integrative Medicine
1.4 Benefits of Integrative Medicine
1.5 Barriers to Implementation
1.6 Conclusions
References
2. Complementary and Alternative Medicines (CAM) vs. Integrative Medicines (IM)Sumera Banoo Malik and Ekta Nehra
2.1 Introduction
2.2 Complementary and Alternative Medicine (CAM) and Integrative Medicine (IM): Definitions and Classification
2.2.1 Definition of CAM
2.2.2 Types of CAM
2.2.3 Integrative Medicine (IM)
2.3 How Can We Progress Towards IM?
2.4 Movement Towards Change in Medical System
2.5 Need of CAM and Conventional Medical System in Integrative Medicine
2.6 Influences on the Successful Integration of CAM and Conventional Medicine
2.7 Increase in the Popularity and Public Awareness Regarding CAM: A Way for IM Development
2.8 Risks of Complementary and Alternative Medicine During IM Usage
2.8.1 Risks Due to Variability
2.8.2 Information Variability
2.8.3 Risks Due to an Assumption
2.8.4 Risks Due to Opportunity Cost
2.8.5 Economic Risk
2.8.6 Fear of Disclosure
2.9 IM: A Shift in Paradigm
2.10 Use of CAM and IM to Combat Various Health Complications
2.10.1 CAM in Breast Cancer Patients
2.10.2 CAM in COVID-19
2.10.3 Use of CAM in Liver Disease
2.10.4 CAM Approaches to the Neurobiology of Acupuncture
2.10.5 Integrative Oncology
2.10.6 Integrative Medicine in COVID-19
2.11 Future of IM
2.12 Suggested Strategy for Integrating CAM into Primary Care: Development of IM
2.12.1 The Patient
2.12.2 The CAM Provider
2.12.3 The Physician
2.13 Conclusions
Acknowledgement
References
3. A Multidimensional Approach: Evaluating the Role of Integrative Medicine for the Management of COVID-19Shahid Nazir Wani, Amarjot Kaur Grewal, Amit Kumar, Ishrat Zahoor, Ahsan Ali and Shahbaz Eqbal
3.1 Introduction
3.2 Understanding COVID-19 and Available Treatment Approaches
3.3 Integrated Medicine: A Holistic Approach for COVID-19 Management
3.4 Complementary and Alternative Medicine (CAM) Modalities
3.4.1 Traditional Herbal Remedies
3.4.2 Acupuncture and Acupressure
3.4.3 Mind-Body Practices (Yoga, Meditation, Tai Chi)
3.4.4 Ayurveda and Traditional Chinese Medicine (TCM)
3.4.5 Homeopathy
3.4.6 Nutritional and Dietary Interventions
3.5 Synergistic Effects of CAM and Conventional Treatments
3.6 Safety and Efficacy Considerations
3.7 Clinical Status of Integrative Medicine for COVID-19
3.8 Future Directions and Recommendations
3.9 Conclusion
Acknowledgements
References
4. Integrative Approaches to Treat Ischemic Heart Disease or Coronary Artery DiseaseKhalida Bashir
4.1 Introduction
4.2 Epidemiology
4.3 Cardiovascular Diseases
4.4 Pathogenesis of Cardiovascular Diseases
4.5 Integrative Medicine in Ischeamic Heart Diseases/Cardiovascular Diseases
4.6 Dietary Considerations in Coronary Artery Disease (CAD)
4.6.1 Dietary Recommendations
4.6.2 Dietary Consideration for the Prevention of Hypertension
4.7 Wellness Revolution and Lifestyle Changes
4.7.1 How to Start Healing?
4.8 A Holistic Cardiology and Functional Medicinal Approach
4.9 Limitations
4.10 Conclusion
References
5. Integrative Medicine’s Approach to Prevent StrokeSonia Thapa, Manmeet Kour and Shashank K. Singh
5.1 Introduction
5.2 Integrative Medicine Approaches to Reduce Stroke and Cardiovascular Risk
5.2.1 Stroke
5.2.1.1 Risk Elements for Stroke
5.2.1.2 Ischemic Stroke
5.2.1.3 Ischemic Anterior Circulation Stroke
5.2.1.4 Posterior Circulation Ischemic Stroke
5.2.2 Mechanism-Based Classification
5.2.2.1 Hemodynamic Compromise
5.2.2.2 Embolism
5.2.2.3 Thrombosis
5.3 Principles of Integrative Medicine
5.3.1 Doctor-Patient Relationship
5.3.2 Wellness and Healing
5.3.3 Inclusiveness
5.4 Role of Lifestyle Modification
5.4.1 Salt
5.4.2 Smoking
5.4.3 Obesity
5.4.4 Alcohol
5.4.5 Food
5.5 Stress Management
5.6 Herbal and Nutritional Supplements
5.7 Acupuncture and Traditional Chinese Medicine
5.8 Perspectives of Clinical Studies in Integrative Medicine
5.9 Challenges and Future Directions in Integrative Medicine
5.10 Conclusion
Acknowledgement
References
6. Integrated Approach to Decrease Respiratory Tract InfectionAnees Akhtar, S. Zeeshan Ahmad Hashmi, Adil Raza and Nazish Fatima
6.1 Introduction
6.2 Understanding the Respiratory Tract Infection
6.2.1 Upper Respiratory Tract Infection (URTI)
6.2.2 Lower Respiratory Tract Infection (LRTI)
6.3 Transmission Modes of Respiratory Tract Infections
6.3.1 Droplet Transmission
6.3.2 Airborne Transmission
6.3.3 Contact Transmission
6.3.4 Fomite Transmission
6.3.5 Vertical Transmission
6.3.6 Droplet Nuclei Transmission
6.3.7 Feco-Oral Transmission
6.4 Risk Factors for Respiratory Tract Infection
6.5 The Integrated Approach
6.5.1 Vaccination Programs
6.5.1.1 Routine Vaccination
6.5.1.2 Adult Vaccination
6.5.1.3 Travel Vaccination
6.5.1.4 Annual Vaccination
6.5.1.5 Community Immunity (Herd Immunity)
6.5.2 Hygiene
6.5.2.1 Hand Hygiene
6.5.2.2 Respiratory Hygiene (Cough Etiquette)
6.5.2.3 General Hygiene Practices
6.6 Air Quality Improvement
6.6.1 Ventilation Strategies
6.6.2 Environmental Control in Healthcare Settings
6.6.2.1 Air Filtration in Healthcare Settings
6.6.3 Public Spaces and Transportation
6.7 Diagnosis and Clinical Assessment
6.7.1 Appropriate Antibiotic Prescribing
6.7.2 Duration of Treatment
6.7.3 Patient Education
6.7.4 Antibiotic Resistance Surveillance
6.7.5 Use of Rapid Diagnostic Tests
6.7.6 Research and Development
6.8 Smoking Cessation Programs
6.9 Physical Activity and Nutrition
6.10 Disease Surveillance Systems
6.11 Data Collection and Analysis
6.12 Early Detection and Response Strategies
6.13 Specific Case Studies
6.14 Challenges and Future Directions
6.15 Conclusion
References
7. Integrative Medicine to Treat Tracheae, Bronchus, and Lung CancerIshrat Zahoor, Rajni Bala, Sukhbir Singh, Neelam Sharma, Samrat Chauhan, Shahid Nazir Wani, Ahsan Ali and Priya Dhiman
7.1 Introduction
7.2 Understanding Trachea, Bronchus, and Lung Cancer Epidemiology and Incidence
7.3 Types of Lung Cancer
7.3.1 Adenocarcinoma
7.3.2 Squamous Cell Carcinoma
7.3.3 Large Cell Carcinoma
7.4 Stages of Lung Cancer
7.4.1 Stage I
7.4.2 Stage II
7.4.3 Stage III
7.4.4 Stage IV
7.5 Conventional Treatment Modalities
7.5.1 Surgery and Radiotherapy
7.5.2 Chemotherapy
7.6 Integrative Medicine to Treat Tracheae, Bronchus, and Lung Cancer
7.6.1 Lifestyle Modifications
7.6.1.1 Exercise as Medication
7.6.1.2 Diet
7.6.1.3 Sleep
7.6.1.4 Stress
7.6.2 Mind-Body Interventions
7.6.2.1 Massage Therapy
7.6.2.2 Acupuncture
7.6.2.3 Mindfulness-Based Interventions
7.6.2.4 Tai Chi
7.6.2.5 Yoga
7.6.3 Natural Products
7.7 Conclusion
References
8. Integrative Approach Towards Treatment of Alzheimer’s and Other DementiasNihad Ashraf Khan, Niti Sambyal, Tanzeelah, Punya Sachdeva, Deepali Siwan, Andleeb Rehman, Anuvab Dey, Subhrojyoti Ghosh, Atharva Anand Mahajan, Saliha Rizvi and Gowhar Rashid
8.1 Introduction
8.2 Neurodegenerative Diseases: Key Elements of Alzheimer’s and Other Dementias
8.2.1 Molecular Neuropathological Features of Alzheimer’s Disease
8.2.1.1 Amyloid Plaques
8.2.1.2 Neurofibrillary Tangles and Neuropil Threads
8.2.1.3 Cerebral Amyloid Angiopathy (CAA)
8.2.1.4 Granulovacuolar Degeneration (GVD) and Hirano Bodies
8.2.1.5 Neuronal and Synaptic Loss
8.2.1.6 Glial Response
8.2.2 Pathophysiological Characteristics of AD
8.2.2.1 Genetic Risk Factors for AD
8.2.2.2 Amyloid Precursor Protein (APP)
8.2.2.3 Presenilins
8.2.2.4 Non-Genetic Risk Factors for AD
8.2.2.5 Hypercholesterolemia and High-Density Lipoprotein Cholesterol
8.2.2.6 Mitochondrial Dysfunction and Oxidative Stress
8.2.2.7 Insulin and Cholinergic Hypothesis
8.2.2.8 Tauopathy: A Main Trait of AD and Other Dementias
8.3 Several Biomarkers Involved in the Early Diagnosis of Alzheimer’s Disease
8.3.1 Cerebrospinal Fluid Biomarkers
8.3.1.1 Amyloid Precursor Protein (APP), Aβ, Truncated Aβ Biomarkers
8.3.1.2 Tau Biomarker
8.3.2 Blood Biomarkers
8.3.3 Inflammatory Biomarkers
8.3.4 Synaptic Biomarkers
8.3.4.1 Neurogranin
8.3.4.2 NFL
8.3.4.3 α-Syn
8.3.5 Urine/Saliva/Tear Biomarkers
8.4 Prominent Mechanisms Involved in AD Therapy
8.4.1 Gene Therapies
8.4.1.1 Vector-Based Gene Therapy
8.4.1.2 Other Therapeutic Mechanisms Involved in AD
8.4.2 Aggregation of Insulin in AD
8.5 Integrative Approaches: Treatment of Alzheimer’s Disease
8.5.1 Role of Chaperones and Mitochondria-AD Therapeutic Approach
8.5.2 Role of Glucose and Cholesterol Involved in AD Therapy
8.6 Pharmacological and Non-Pharmacological Approaches to Treat AD and Other Dementias
8.6.1 Pharmacological Treatments
8.6.1.1 Treatment Targeting Acetylcholinesterase
8.6.1.2 Additional Novel Pharmacological Strategies for Modulating Aβ and Tau Protein Levels
8.6.1.3 C2N-8E12
8.6.2 Non-Pharmacological Treatment for AD
8.6.2.1 Ketogenic Diet for AD
8.6.2.2 Consumption of Fruits and Vegetables
8.6.2.3 Dairy Products
8.6.2.4 Coffee Consumption
8.6.2.5 Turmeric (Curcumal longa)
8.6.3 Other Types of Dementia and Treatment Strategies
8.7 Role of NSAIDs and Statins in the Treatment of Alzheimer’s Disease
8.8 Preventive Measures: Alzheimer’s Disease and Other Dementias
8.8.1 Sustainable Resource
8.8.2 Aerobic Workouts
8.8.3 Nutrition
8.8.4 Vitamin D
8.8.5 Estrogen (Hormone Replacement Therapy)
8.9 Conclusion
References
9. Integrative Approaches to Minimize Dehydration Due to Diarrheal DiseasesImran Ali Khan
9.1 Introduction
9.2 Causes of Diarrhea
9.3 Dehydration
9.4 Types of Diarrhea
9.5 Diarrhoea Types Caused by Infections
9.6 Rotavirus
9.7 Symptoms
9.8 Treatment
9.9 Immune System
9.10 Integrative Methods to Reduce Diarrhoeal Disease
9.11 Conclusion
References
10. Integrative Approaches to Treat TuberculosisYashodhara Goswami, Yugal Kishore Mohanta and Ishani Chakrabartty
10.1 Introduction
10.2 Causal Organism of Tuberculosis
10.3 Detection and Diagnostics of Tuberculosis
10.4 Treatment of Tuberculosis
10.5 Integrative Approach to Treat Tuberculosis
10.5.1 Drug-Based Approaches
10.5.1.1 Drugs to Treat Tuberculosis and Their Anti-Tuberculous Target Activities
10.5.1.2 Drugs from Natural Resources
10.5.2 Surgical Measures
10.6 Preventive Measures for Tuberculosis
10.7 Importance of Social Determinants in the Treatment of Tuberculosis
10.8 Conclusion
Acknowledgement
References
11. Integrative Approaches to Treat CirrhosisMehboob Ali and Sakina Banoo
11.1 Introduction
11.2 Different Integrative Approaches Against Cirrhosis
11.2.1 Dietary Modifications
11.2.1.1 Sodium Restriction
11.2.1.2 Protein Adjustment
11.2.1.3 Fluid Management
11.2.1.4 Alcohol Avoidance
11.2.1.5 Balanced Nutrition
11.2.1.6 Monitoring Nutrient Deficiencies
11.2.2 Herbal and Nutritional Supplements
11.2.2.1 Milk Thistle (Silymarin)
11.2.2.2 S-Adenosyl-L-Methionine (SAMe)
11.2.2.3 Probiotics
11.2.2.4 Omega-3 Fatty Acids
11.2.2.5 Vitamin E
11.2.3 Acupuncture and Traditional Chinese Medicine (TCM)
11.2.4 Mind-Body Techniques
11.2.4.1 Stress Reduction and Relaxation Techniques
11.2.4.2 Mindfulness-Based Stress Reduction (MBSR)
11.2.4.3 Yoga and Tai Chi
11.2.4.4 Cognitive-Behavioral Therapy (CBT)
11.2.4.5 Guided Imagery
11.2.5 Exercise and Physical Activity
11.2.5.1 Improve Physical Fitness
11.2.5.2 Weight Management
11.2.5.3 Enhance Energy Levels
11.2.5.4 Improve Mental Well-Being
11.2.5.5 Social Engagement and Support
11.3 Conclusion
References
12. Recent Advancements in the Field of Biotechnology for Integrative Medicine (IM)Quazi Mohammad Imranul Haq, Ghulam Abbas and Issa Sulaiman Al-Amri
12.1 Introduction
12.2 Biotechnological Approaches for Herbal Drug Production
12.2.1 Plant Tissue Culture
12.2.2 Genetic Engineering
12.2.3 Metabolic Engineering
12.2.4 Elicitation
12.3 Traditional Medicine
12.3.1 Traditional Chinese Medicine (TCM)
12.3.2 Ayurvedic Medicine
12.3.3 Native American Medicine
12.3.4 Traditional African Medicine
12.3.5 Ancient Systems of Medicine
12.4 Conclusion
References
13. Advantages and Future Prospective of Integrative MedicinesMohammad Asif Siddiqui, Shivam Chowdhary, Lavina Vaswani and Ayesha G. Siddiqui
13.1 Introduction
13.2 Components of Integrative Medicine
13.2.1 Biological Therapies
13.2.1.1 Phytotherapy
13.2.1.2 Trophotherapy
13.2.1.3 Aromatherapy
13.2.2 Energy-Based Therapy
13.2.2.1 Acupuncture
13.2.2.2 Zone Therapy
13.2.2.3 Tai Chi
13.2.3 Physical Manipulation Therapy
13.2.3.1 Osteopathy and Chiropractic
13.2.3.2 Reiki
13.2.3.3 Massage Therapy
13.2.4 Alternative Medical System
13.2.4.1 Ayurveda
13.2.4.2 Homeopathy Medicine and Homotoxicology
13.2.5 Mind-Body Manipulation Therapy
13.2.5.1 Yoga and Meditation Therapy
13.2.5.2 Musicotherapy
13.3 Advantages of Integrative Medicine Components
13.3.1 Phytotherapy
13.3.1.1 Advantages of Phytotherapy Components
13.3.2 Advantages of Trophotherapy
13.3.3 Advantages of Aromatherapy
13.3.4 Advantages of Acupuncture
13.3.5 Advantages of Zone Therapy (Foot Reflexology)
13.3.6 Advantages of Tai Chi
13.3.7 Advantages of Osteopathy
13.3.8 Advantages of Chiropathy
13.3.9 Advantages of Massage Therapy
13.3.10 Advantages of Reiki
13.3.11 Advantages of Yoga and Meditation
13.3.12 Advantages of Music Therapy
13.4 Practice and Administering of Integrated Medicine in the Health Sector
13.5 Effectiveness of Integrative Medicine
13.6 Future Prospects of Integrative Medicine
13.7 Disadvantages of Integrative Medicines
13.8 Conclusion
References
About the Editors
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