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Submit a ProposalAdhesives in Biomedical Applications
 | Edited by K.L. Mittal and S. Neogi
Series: Adhesion and Adhesives: Fundamental and Applied Aspects Copyright: 2023 | Status: Published ISBN: 9781394209200 | Hardcover | 338 pages | 48 illustrations Price: $195 USD  |
One Line Description
Uniquely provides up-to-date and comprehensive information on adhesives in biomedical applications in an easily accessible form.
Audience
The book will be used by adhesionists, adhesive technologists, polymer scientists, materials scientists, as well as those involved with biomedical devices and bioimplants such as medical doctors, surgeons, cosmetologists, as well as engineers in the pharmaceutical industry,
The book will be used by adhesionists, adhesive technologists, polymer scientists, materials scientists, as well as those involved with biomedical devices and bioimplants such as medical doctors, surgeons, cosmetologists, as well as engineers in the pharmaceutical industry,
Description
Adhesives are gaining popularity in many and varied biomedical applications as they are being used as a replacement for sutures and staples, which have the disadvantages such as scarring, infection, keloid formation, poor skin healing, or hernia in the case of abdominal sutures. On the other hand, adhesives dramatically reduce healthcare costs, significantly reduce time spent in surgery, curb the risks of bleeding, and are generally easy to use. Adhesives also find their use in diagnostic imaging, various biomedical devices, dental adhesives, dermal adhesives, etc.
Adhesives in Biomedical Applications contains eleven chapters and is divided into two parts: Part 1: General Topics; and Part 2: Specific Adhesives, Characteristics, and Applications. Topics covered include: historical developments of various adhesives for biomedical applications; global industry development and analysis of adhesives for biomedical applications; biomedical adhesives; bioadhesion: fundamentals and mechanisms; fibrin glue; herbal bioactives-based mucoadhesive drug delivery systems; adhesive hydrogels; adhesives in dermal patches; medical adhesives from extracted mussel adhesive proteins; dental adhesives; and the role of adhesive-based systems for diagnostic imaging and theranostic applications.
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Adhesives are gaining popularity in many and varied biomedical applications as they are being used as a replacement for sutures and staples, which have the disadvantages such as scarring, infection, keloid formation, poor skin healing, or hernia in the case of abdominal sutures. On the other hand, adhesives dramatically reduce healthcare costs, significantly reduce time spent in surgery, curb the risks of bleeding, and are generally easy to use. Adhesives also find their use in diagnostic imaging, various biomedical devices, dental adhesives, dermal adhesives, etc.
Adhesives in Biomedical Applications contains eleven chapters and is divided into two parts: Part 1: General Topics; and Part 2: Specific Adhesives, Characteristics, and Applications. Topics covered include: historical developments of various adhesives for biomedical applications; global industry development and analysis of adhesives for biomedical applications; biomedical adhesives; bioadhesion: fundamentals and mechanisms; fibrin glue; herbal bioactives-based mucoadhesive drug delivery systems; adhesive hydrogels; adhesives in dermal patches; medical adhesives from extracted mussel adhesive proteins; dental adhesives; and the role of adhesive-based systems for diagnostic imaging and theranostic applications.
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Author / Editor Details
Kashmiri Lal Mittal was employed by the IBM Corporation from 1972 through 1993. Currently, he is teaching and consulting worldwide in the broad areas of adhesion as well as surface cleaning. He has received numerous awards and honors including the title of
doctor honoris causa from Maria Curie-Skłodowska University, Lublin, Poland. He is the editor of more than 150 books dealing with adhesion measurement, adhesion of polymeric coatings, polymer surfaces, adhesive joints, adhesion promoters, thin films, polyimides, surface modification surface cleaning, and surfactants.
Kashmiri Lal Mittal was employed by the IBM Corporation from 1972 through 1993. Currently, he is teaching and consulting worldwide in the broad areas of adhesion as well as surface cleaning. He has received numerous awards and honors including the title of
doctor honoris causa from Maria Curie-Skłodowska University, Lublin, Poland. He is the editor of more than 150 books dealing with adhesion measurement, adhesion of polymeric coatings, polymer surfaces, adhesive joints, adhesion promoters, thin films, polyimides, surface modification surface cleaning, and surfactants.
S. Neogi, PhD, is a full professor in the Department of Chemical Engineering, Indian Institute of Technology, Kharagpur, West Bengal, India. He gained his PhD from Ohio University and spent 10 years in industry in the U.S. He has about 70 research articles to his name as well as four patents granted.
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Table of Contents
Preface
Part 1: General Topics
1. Historical Developments of Various Adhesives for Biomedical Applications
Nagavendra Kommineni, Raju Saka, Vaskuri G. S. Sainaga Jyothi, Arun Butreddy,
Jyotsna G. Vitore and Wahid Khan
1.1 Origin of Adhesives
1.2 Prominence of Biomedical Adhesives in Wound Healing and Drug Delivery
1.2.1 Wound Healing
1.2.2 Drug Delivery
1.3 Generations of Bioadhesives
1.4 Timeline of Developments and Advances
1.5 Current and Future Applications
1.5.1 Wound Healing
1.5.2 Drug Delivery
1.5.3 Tissue Engineering
1.6 Summary
References
2. Global Industry Development and Analysis of Adhesives for Biomedical Applications
Muhammed Yusuf Kandur, R. Hemamalini and Ebru Toksoy Öner
2.1 Introduction
2.2 Research Landscape of Bioadhesives
2.3 Sources of Bioadhesives for Biomedical Applications
2.3.1 Natural Bioadhesives
2.3.1.1 Protein Bioadhesives
2.3.1.2 Carbohydrate-Based Bioadhesives
2.3.2 Synthetic Adhesives
2.3.2.1 Poly(ethylene glycol)
2.3.2.2 Polycyanoacrylate
2.3.2.3 Chondroitin Sulfate
2.4 Biomedical Applications of Bioadhesives
2.5 Latest Industrial Developments
2.5.1 Novel Adhesives
2.6 Summary
Acknowledgment
References
3. Biomedical Adhesives
Jaehun Mun and Sungbaek Seo
3.1 Introduction
3.1.1 Definition of a Biomedical Adhesive
3.1.2 Proposed Mechanisms of Adhesion
3.1.2.1 Mechanical Interlocking
3.1.2.2 Electrostatic Attraction
3.1.2.3 Adsorption
3.1.2.4 Diffusion
3.1.2.5 Chemical Bonding
3.1.2.6 Weak Boundary Layers
3.1.3 Considerations for Development of Biomedical Adhesives
3.2 Types of Biomedical Adhesives and their Components
3.2.1 Soft Tissue Adhesives
3.2.1.1 Cyanoacrylate-Based Adhesives
3.2.1.2 Fibrin Glue-Based Adhesives
3.2.1.3 Protein-Based Adhesives
3.2.1.4 Polyurethane-Based Adhesives
3.2.1.5 Poly(ethylene glycol) (PEG)-Based Adhesives
3.2.1.6 Mussel-Derived Protein-Based Adhesives
3.2.2 Hard Tissue Adhesives
3.2.2.1 Dental Cement
3.2.2.2 Bone Cements
3.3 Advances in Adhesives Development for Biomedical Uses
3.3.1 Bioglue in Surgery
3.3.2 Wound Dressing
3.4 Summary
3.5 Acknowledgements
References
4. Bioadhesion: Fundamentals and Mechanisms
Amit Porwal and Kamla Pathak
4.1 Introduction
4.2 Bioadhesion in Biological Systems
4.3 Bioadhesion/Mucoadhesion
4.3.1 Specific and Nonspecific Bioadhesion
4.4 The Mucosal Layer and Barriers to Drug Delivery
4.5 Barriers to Mucosal Drug Delivery
4.6 Factors Affecting Mucoadhesion
4.6.1 Bioadhesive Interactions
4.7 Mechanisms of Bioadhesion
4.7.1 Interface Energetics
4.7.2 Chemical Interactions
4.7.3 Mechanical Effects
4.8 Theories of Bioadhesion
4.8.1 Wetting Theory of Bioadhesion
4.8.2 Electrostatic Theory of Bioadhesion
4.8.3 Diffusion Theory of Bioadhesion
4.8.4 Adsorption Theory of Bioadhesion
4.8.5 Fracture Theory of Bioadhesion
4.9 Stages of Mucoadhesion
4.10 Modulation of Mucoadhesion
4.11 Molecular Biology in Bioadhesion
4.12 Administration of Bio- and Mucoadhesive Drug Delivery Systems
4.13 Prospects
4.14 Summary
References
Part 2: Specific Adhesives, Characteristics and Applications
5. Fibrin Glue: Sources, Characteristics and Applications
Anindya Karmaker and Shoeb Ahmed
5.1 Introduction
5.2 Evolution of Fibrin Glue
5.3 Types of Fibrin Adhesives and their Working Mechanisms
5.4 Production Methods of Commercial Fibrin Adhesives
5.5 Comparison of Some Commercial Fibrin Adhesives
5.6 Recent Developments and Future Trend of Fibrin Adhesives
5.7 Summary
References
6. Herbal Bioactives-Based Mucoadhesive Drug Delivery Systems
Shristhi Sohan Rawat, Arya Rai, Deepika Raina and Inderbir Singh
6.1 Introduction
6.2 Mucous Membrane
6.3 Theories of Adhesion
6.3.1 Electronic Theory
6.3.2 Adsorption Theory
6.3.3 Wetting Theory
6.3.4 Diffusion Theory
6.3.5 Fracture Theory
6.4 Mucoadhesive Polymers
6.5 Mucoadhesive-Based Drug Delivery Systems (DDS): Administration Routes
6.5.1 Ocular Mucoadhesive DDS
6.5.2 Nasal DDS
6.5.3 Oromucosal DDS
6.5.4 Pulmonary Mucoadhesive DDS
6.5.5 Gastrointestinal Tract Mucoadhesive DDS
6.5.6 Vaginal Mucosal DDS
6.5.7 Rectal Mucoadhesive DDS
6.6 Clinical Studies
6.7 Patents on Herbal Bioactive–Based Mucoadhesive Drug Delivery Systems
6.8 Summary
References
7. Adhesive Hydrogels
Proma Bhattacharya and Sudarsan Neogi
7.1 Introduction
7.1.1 Hydrogels
7.1.2 Conventional Adhesives in Biomedicine
7.1.3 Need for Adhesive Hydrogels
7.2 Mechanisms of Adhesion
7.2.1 Mechanical Interlocking
7.2.2 Wet Adhesion
7.2.3 Diffusion
7.2.4 van der Waals Force
7.2.5 Electrostatic Interaction
7.2.6 π-π Interaction
7.2.7 Hydrogen Bonding
7.2.8 Ionic and Covalent Bonding
7.3 Design Principles for Adhesive Hydrogels
7.4 Commonly Used Adhesive Hydrogels
7.4.1 Natural Polysaccharides
7.4.2 Poly(amino acid)s and Their Analogues
7.4.3 Adhesive Proteins
7.4.4 Synthetic Polymers
7.5 Prospective Applications of Adhesive Hydrogels
7.5.1 Biomedicine
7.5.2 Textiles
7.5.3 Food Science
7.5.4 Bioelectronics
7.5.5 Cosmetics
7.6 Summary
References
8. Adhesives in Dermal Patches
Niharika Lal, Praveen Kumar Gaur and Navneet Verma
8.1 Introduction
8.2 Types of Dermal Patches
8.2.1 Microreservoir Type Dermal Patches
8.2.2 Adhesive Dispersion Controlled Dermal Patches
8.2.3 Membrane Permeation Controlled Dermal Patches
8.2.4 Matrix Diffusion Controlled Dermal Patches
8.3 Evolution of Adhesives in Medical Applications
8.4 Types of Adhesives Used in Dermal Patches
8.4.1 PIB-Based PSAs
8.4.2 Silicone-Based PSAs
8.4.3 Acrylic PSAs
8.4.4 Other PSAs
8.5 Testing Physical Properties of PSAs
8.5.1 Tack Test
8.5.2 Shear Adhesion or Creep Test
8.5.3 Peel Resistance Test
8.6 Prediction of Patch In Vivo Adhesive Performances
8.7 Adhesive Properties and Formulation Studies
8.8 Summary
Acknowledgements
References
9. Medical Adhesives from Extracted Mussel Adhesive Proteins
Yuvaraj Dinakarkumar, Annushrie Arravind and Niranjana Murali Mohan
9.1 Introduction
9.2 The Mussel Byssus
9.2.1 Collagenous Thread Protein
9.2.2 Thread Matrix Protein
9.2.3 Mussel Foot Proteins (MFPs)
9.3 Mussel-Inspired Adhesion
9.3.1 History
9.3.2 Bioadhesives
9.3.2.1 Mechanisms of Biological Tissue Adhesion
9.3.3 Role of DOPA in Adhesion Process
9.3.3.1 DOPA Oxidation
9.3.3.2 Coacervation
9.3.3.3 Surface Drying
9.3.3.4 Catechol Modification
9.4 Mussel-Inspired Tissue Adhesives
9.4.1 Extraction of Mussel Protein
9.4.2 Synthesis of Catechol-Functionalized Polymers
9.4.2.1 Direct Functionalization
9.4.2.2 Polymerization of Modified Monomers
9.4.2.3 Methods to Synthesize Catechol Peptides
9.4.2.4 Recombinant Technology
9.4.3 Mussel-Inspired Medical Bioadhesives
9.4.3.1 Bioglues
9.4.3.2 Drug Delivery
9.4.3.3 Tissue Engineering
9.4.3.4 Cellular Engineering
9.5 Summary
References
10. Dental Adhesives: State-of-the-Art, Current Perspectives, and Promising Applications
Lamia Sami Mokeem, Isadora Martini Garcia, Abdulrahman A. Balhaddad, Kevin Cline, Gabriel Rakovsky, Fabrício Mezzomo Collares and Mary Anne S. Melo
10.1 Introduction
10.2 Brief History of Dental Adhesive Systems
10.3 Classification and Composition of Adhesive Systems
10.3.1 Three-Step Etch-and-Rinse Conventional Adhesive System
10.3.2 Two-Step Etch-and-Rinse Conventional Adhesive System
10.3.3 Two-Step Self-Etch Adhesive System
10.3.4 One-Step Self-Etch Adhesive System
10.3.5 Universal or Multimode Adhesive System
10.4 Understanding the Challenges of Dental Adhesives Inside the Mouth
10.4.1 Host-Derived Proteolytic Enzymes
10.4.2 Adverse Chemical/Biochemical Interactions
10.4.3 Mechanical Loading
10.5 New Approaches Targeting Longevity of Adhesive-Dentin Interfaces
10.6 Dental Adhesives Endowed With Antibacterial Properties
10.7 Summary
10.8 Acknowledgments
References
11. Role of Adhesive-Based Systems for Diagnostic Imaging and Theranostic Applications
Aishee Dey and Sudarsan Neogi
11.1 Introduction
11.2 Role of Adhesives in Diagnostic Imaging
11.2.1 X-Ray Imaging
11.2.2 Magnetic Resonance Imaging
11.2.3 Ultrasound Imaging
11.2.4 Endoscopy
11.2.5 Fluorescence Imaging
11.2.6 Other Applications
11.3 Theranostics
11.3.1 DOPA (3,4-dihydroxyl-L-phenylalanine) and Dopamine
11.3.2 Gelatin
11.3.3 Chitosan
11.3.4 Poly(lactic-co-glycolic acid)
11.3.5 Poly(acrylic acid)
11.4 Summary
References
Index
Back to Top
Preface
Part 1: General Topics
1. Historical Developments of Various Adhesives for Biomedical Applications
Nagavendra Kommineni, Raju Saka, Vaskuri G. S. Sainaga Jyothi, Arun Butreddy,
Jyotsna G. Vitore and Wahid Khan
1.1 Origin of Adhesives
1.2 Prominence of Biomedical Adhesives in Wound Healing and Drug Delivery
1.2.1 Wound Healing
1.2.2 Drug Delivery
1.3 Generations of Bioadhesives
1.4 Timeline of Developments and Advances
1.5 Current and Future Applications
1.5.1 Wound Healing
1.5.2 Drug Delivery
1.5.3 Tissue Engineering
1.6 Summary
References
2. Global Industry Development and Analysis of Adhesives for Biomedical Applications
Muhammed Yusuf Kandur, R. Hemamalini and Ebru Toksoy Öner
2.1 Introduction
2.2 Research Landscape of Bioadhesives
2.3 Sources of Bioadhesives for Biomedical Applications
2.3.1 Natural Bioadhesives
2.3.1.1 Protein Bioadhesives
2.3.1.2 Carbohydrate-Based Bioadhesives
2.3.2 Synthetic Adhesives
2.3.2.1 Poly(ethylene glycol)
2.3.2.2 Polycyanoacrylate
2.3.2.3 Chondroitin Sulfate
2.4 Biomedical Applications of Bioadhesives
2.5 Latest Industrial Developments
2.5.1 Novel Adhesives
2.6 Summary
Acknowledgment
References
3. Biomedical Adhesives
Jaehun Mun and Sungbaek Seo
3.1 Introduction
3.1.1 Definition of a Biomedical Adhesive
3.1.2 Proposed Mechanisms of Adhesion
3.1.2.1 Mechanical Interlocking
3.1.2.2 Electrostatic Attraction
3.1.2.3 Adsorption
3.1.2.4 Diffusion
3.1.2.5 Chemical Bonding
3.1.2.6 Weak Boundary Layers
3.1.3 Considerations for Development of Biomedical Adhesives
3.2 Types of Biomedical Adhesives and their Components
3.2.1 Soft Tissue Adhesives
3.2.1.1 Cyanoacrylate-Based Adhesives
3.2.1.2 Fibrin Glue-Based Adhesives
3.2.1.3 Protein-Based Adhesives
3.2.1.4 Polyurethane-Based Adhesives
3.2.1.5 Poly(ethylene glycol) (PEG)-Based Adhesives
3.2.1.6 Mussel-Derived Protein-Based Adhesives
3.2.2 Hard Tissue Adhesives
3.2.2.1 Dental Cement
3.2.2.2 Bone Cements
3.3 Advances in Adhesives Development for Biomedical Uses
3.3.1 Bioglue in Surgery
3.3.2 Wound Dressing
3.4 Summary
3.5 Acknowledgements
References
4. Bioadhesion: Fundamentals and Mechanisms
Amit Porwal and Kamla Pathak
4.1 Introduction
4.2 Bioadhesion in Biological Systems
4.3 Bioadhesion/Mucoadhesion
4.3.1 Specific and Nonspecific Bioadhesion
4.4 The Mucosal Layer and Barriers to Drug Delivery
4.5 Barriers to Mucosal Drug Delivery
4.6 Factors Affecting Mucoadhesion
4.6.1 Bioadhesive Interactions
4.7 Mechanisms of Bioadhesion
4.7.1 Interface Energetics
4.7.2 Chemical Interactions
4.7.3 Mechanical Effects
4.8 Theories of Bioadhesion
4.8.1 Wetting Theory of Bioadhesion
4.8.2 Electrostatic Theory of Bioadhesion
4.8.3 Diffusion Theory of Bioadhesion
4.8.4 Adsorption Theory of Bioadhesion
4.8.5 Fracture Theory of Bioadhesion
4.9 Stages of Mucoadhesion
4.10 Modulation of Mucoadhesion
4.11 Molecular Biology in Bioadhesion
4.12 Administration of Bio- and Mucoadhesive Drug Delivery Systems
4.13 Prospects
4.14 Summary
References
Part 2: Specific Adhesives, Characteristics and Applications
5. Fibrin Glue: Sources, Characteristics and Applications
Anindya Karmaker and Shoeb Ahmed
5.1 Introduction
5.2 Evolution of Fibrin Glue
5.3 Types of Fibrin Adhesives and their Working Mechanisms
5.4 Production Methods of Commercial Fibrin Adhesives
5.5 Comparison of Some Commercial Fibrin Adhesives
5.6 Recent Developments and Future Trend of Fibrin Adhesives
5.7 Summary
References
6. Herbal Bioactives-Based Mucoadhesive Drug Delivery Systems
Shristhi Sohan Rawat, Arya Rai, Deepika Raina and Inderbir Singh
6.1 Introduction
6.2 Mucous Membrane
6.3 Theories of Adhesion
6.3.1 Electronic Theory
6.3.2 Adsorption Theory
6.3.3 Wetting Theory
6.3.4 Diffusion Theory
6.3.5 Fracture Theory
6.4 Mucoadhesive Polymers
6.5 Mucoadhesive-Based Drug Delivery Systems (DDS): Administration Routes
6.5.1 Ocular Mucoadhesive DDS
6.5.2 Nasal DDS
6.5.3 Oromucosal DDS
6.5.4 Pulmonary Mucoadhesive DDS
6.5.5 Gastrointestinal Tract Mucoadhesive DDS
6.5.6 Vaginal Mucosal DDS
6.5.7 Rectal Mucoadhesive DDS
6.6 Clinical Studies
6.7 Patents on Herbal Bioactive–Based Mucoadhesive Drug Delivery Systems
6.8 Summary
References
7. Adhesive Hydrogels
Proma Bhattacharya and Sudarsan Neogi
7.1 Introduction
7.1.1 Hydrogels
7.1.2 Conventional Adhesives in Biomedicine
7.1.3 Need for Adhesive Hydrogels
7.2 Mechanisms of Adhesion
7.2.1 Mechanical Interlocking
7.2.2 Wet Adhesion
7.2.3 Diffusion
7.2.4 van der Waals Force
7.2.5 Electrostatic Interaction
7.2.6 π-π Interaction
7.2.7 Hydrogen Bonding
7.2.8 Ionic and Covalent Bonding
7.3 Design Principles for Adhesive Hydrogels
7.4 Commonly Used Adhesive Hydrogels
7.4.1 Natural Polysaccharides
7.4.2 Poly(amino acid)s and Their Analogues
7.4.3 Adhesive Proteins
7.4.4 Synthetic Polymers
7.5 Prospective Applications of Adhesive Hydrogels
7.5.1 Biomedicine
7.5.2 Textiles
7.5.3 Food Science
7.5.4 Bioelectronics
7.5.5 Cosmetics
7.6 Summary
References
8. Adhesives in Dermal Patches
Niharika Lal, Praveen Kumar Gaur and Navneet Verma
8.1 Introduction
8.2 Types of Dermal Patches
8.2.1 Microreservoir Type Dermal Patches
8.2.2 Adhesive Dispersion Controlled Dermal Patches
8.2.3 Membrane Permeation Controlled Dermal Patches
8.2.4 Matrix Diffusion Controlled Dermal Patches
8.3 Evolution of Adhesives in Medical Applications
8.4 Types of Adhesives Used in Dermal Patches
8.4.1 PIB-Based PSAs
8.4.2 Silicone-Based PSAs
8.4.3 Acrylic PSAs
8.4.4 Other PSAs
8.5 Testing Physical Properties of PSAs
8.5.1 Tack Test
8.5.2 Shear Adhesion or Creep Test
8.5.3 Peel Resistance Test
8.6 Prediction of Patch In Vivo Adhesive Performances
8.7 Adhesive Properties and Formulation Studies
8.8 Summary
Acknowledgements
References
9. Medical Adhesives from Extracted Mussel Adhesive Proteins
Yuvaraj Dinakarkumar, Annushrie Arravind and Niranjana Murali Mohan
9.1 Introduction
9.2 The Mussel Byssus
9.2.1 Collagenous Thread Protein
9.2.2 Thread Matrix Protein
9.2.3 Mussel Foot Proteins (MFPs)
9.3 Mussel-Inspired Adhesion
9.3.1 History
9.3.2 Bioadhesives
9.3.2.1 Mechanisms of Biological Tissue Adhesion
9.3.3 Role of DOPA in Adhesion Process
9.3.3.1 DOPA Oxidation
9.3.3.2 Coacervation
9.3.3.3 Surface Drying
9.3.3.4 Catechol Modification
9.4 Mussel-Inspired Tissue Adhesives
9.4.1 Extraction of Mussel Protein
9.4.2 Synthesis of Catechol-Functionalized Polymers
9.4.2.1 Direct Functionalization
9.4.2.2 Polymerization of Modified Monomers
9.4.2.3 Methods to Synthesize Catechol Peptides
9.4.2.4 Recombinant Technology
9.4.3 Mussel-Inspired Medical Bioadhesives
9.4.3.1 Bioglues
9.4.3.2 Drug Delivery
9.4.3.3 Tissue Engineering
9.4.3.4 Cellular Engineering
9.5 Summary
References
10. Dental Adhesives: State-of-the-Art, Current Perspectives, and Promising Applications
Lamia Sami Mokeem, Isadora Martini Garcia, Abdulrahman A. Balhaddad, Kevin Cline, Gabriel Rakovsky, Fabrício Mezzomo Collares and Mary Anne S. Melo
10.1 Introduction
10.2 Brief History of Dental Adhesive Systems
10.3 Classification and Composition of Adhesive Systems
10.3.1 Three-Step Etch-and-Rinse Conventional Adhesive System
10.3.2 Two-Step Etch-and-Rinse Conventional Adhesive System
10.3.3 Two-Step Self-Etch Adhesive System
10.3.4 One-Step Self-Etch Adhesive System
10.3.5 Universal or Multimode Adhesive System
10.4 Understanding the Challenges of Dental Adhesives Inside the Mouth
10.4.1 Host-Derived Proteolytic Enzymes
10.4.2 Adverse Chemical/Biochemical Interactions
10.4.3 Mechanical Loading
10.5 New Approaches Targeting Longevity of Adhesive-Dentin Interfaces
10.6 Dental Adhesives Endowed With Antibacterial Properties
10.7 Summary
10.8 Acknowledgments
References
11. Role of Adhesive-Based Systems for Diagnostic Imaging and Theranostic Applications
Aishee Dey and Sudarsan Neogi
11.1 Introduction
11.2 Role of Adhesives in Diagnostic Imaging
11.2.1 X-Ray Imaging
11.2.2 Magnetic Resonance Imaging
11.2.3 Ultrasound Imaging
11.2.4 Endoscopy
11.2.5 Fluorescence Imaging
11.2.6 Other Applications
11.3 Theranostics
11.3.1 DOPA (3,4-dihydroxyl-L-phenylalanine) and Dopamine
11.3.2 Gelatin
11.3.3 Chitosan
11.3.4 Poly(lactic-co-glycolic acid)
11.3.5 Poly(acrylic acid)
11.4 Summary
References
Index
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