This book serves as a bridge connecting the theoretical foundations of DRL with practical, actionable insights for implementing these technologies in a variety of industrial contexts, making it a valuable resource for professionals and enthusiasts at the forefront of technological innovation.
Table of ContentsPreface
1. Deep Reinforcement Learning Applications in Real-World Scenarios: Challenges and OpportunitiesSunilkumar Ketineni and Sheela J.
1.1 Introduction 
1.1.1 Problems with Real-World Implementation 
1.2 Application to the Real World 
1.2.1 Security and Robustness 
1.2.2 Generalization 
1.2.2.1 Overcoming Challenges in DRL 
1.3 Possibilities for Making a Difference in the Real World 
1.3.1 Transfer Learning and Domain Adaptation 
1.4 Meta-Learning 
1.5 Deep Reinforcement Learning (DRL) 
1.5.1 Hybrid Approaches 
1.6 Online vs. Offline Reinforcement Learning 
1.7 Human-in-the-Loop Systems 
1.8 Benchmarking and Standardization 
1.9 Collaborative Multi-Agent Systems 
1.10 Transfer Learning and Domain Adaptation 
1.11 Hierarchical and Multimodal Learning 
1.12 Imitation Learning and Human Feedback 
1.13 Inverse Reinforcement Learning 
1.14 Sim-to-Real Transfer 
1.15 Conclusion 
References 
2. Deep Reinforcement Learning: A Key to Unlocking the Potential of Robotics
and Autonomous SystemsSaksham and Chhavi Rana
2.1 Introduction 
2.1.1 Significance of DRL Field 
2.1.2 Transformative Advantages of DRL Field 
2.2 Fields of Investigation 
2.2.1 General Methods for Investigation 
2.3 Background 
2.3.1 Fundamentals of Deep Reinforcement Learning (DRL) 
2.4 Deep Reinforcement Learning (DRL) in Robot Control 
2.4.1 Navigation and Localization 
2.4.2 Object Manipulation 
2.5 Applications and Case Studies 
2.6 Challenges and Future Directions 
2.7 Evaluation and Metrics 
2.8 Summary 
References 
3. Deep Reinforcement Learning Algorithms: A Comprehensive OverviewShweta V. Bondre, Bhakti Thakre, Uma Yadav and Vipin D. Bondre
3.1 Introduction 
3.1.1 How Reinforcement Learning Works? 
3.2 Reinforcement Learning Algorithms 
3.2.1 Value-Based Algorithms 
3.2.1.1 Q-Learning 
3.2.1.2 Deep Q-Networks (DQN) 
3.2.1.3 Double DQN 
3.2.1.4 Dueling DQN 
3.3 Policy-Based 
3.3.1 Policy Gradient Methods 
3.3.2 REINFORCE (Monte Carlo Policy Gradient) 
3.3.3 Actor–Critic Methods 
3.3.4 Natural Policy Gradient Methods 
3.4 Model-Based Reinforcement Learning 
3.4.1 Probabilistic Ensembles with Trajectory Sampling (PETS) 
3.4.2 Probabilistic Inference for Learning Control (PILCO) 
3.4.3 Model Predictive Control (MPC) 
3.4.4 Model-Agnostic Meta-Learning (MAML) 
3.4.5 Soft Actor–Critic with Model Ensemble 
3.4.6 Deep Deterministic Policy Gradients with Model (DDPG with Model) 
3.5 Characteristics of Reinforcement Learning 
3.6 DRL Algorithms and Their Advantages and Drawbacks 
3.7 Conclusion 
References 
4. Deep Reinforcement Learning in Healthcare and Biomedical Applications Balakrishnan D., Aarthy C., Nandhagopal Subramani, Venkatesan R. and Logesh T. R.
4.1 Introduction 
4.2 Related Works 
4.3 Deep Reinforcement Learning Framework 
4.4 Deep Reinforcement Learning Applications in Healthcare and Biomedicine 
4.5 Deep Reinforcement Learning Employs Efficient Algorithms 
4.5.1 Deep Q-Networks 
4.5.2 Policy Differentiation Techniques 
4.5.3 Hindsight Experience Replay (HER) 
4.5.4 Curiosity-Driven Exploration 
4.5.5 Long Short-Term Memory Networks and Recurring Neural Network Designs 
4.5.6 Multi-Agent DRL
4.6 Semi-Autonomous Control Based on Deep Reinforcement Learning for Robotic Surgery 
4.6.1 Double Deep Q-Network (DDQN) 
4.6.2 Materials and Methods 
4.6.3 Results 
4.6.4 Discussion 
4.7 Conclusion 
References 
5. Application of Deep Reinforcement Learning in Adversarial Malware DetectionManju and Chhavi Rana
5.1 Introduction 
5.1.1 Background 
5.1.2 Significance of Malware Detection 
5.1.3 Challenges with Adversarial Attacks 
5.2 Foundations of Deep Reinforcement Learning 
5.2.1 Overview of Deep Reinforcement Learning 
5.2.2 Core Concepts and Components 
5.2.3 Relevance to Malware Detection 
5.3 Malware Detection Landscape 
5.3.1 Evolution of Malware Detection Techniques 
5.3.2 Adversarial Attacks in Cybersecurity 
5.3.3 Need for Advanced Detection Strategies 
5.4 Deep Reinforcement Learning Techniques 
5.4.1 Application of Deep Learning in Malware Detection 
5.4.2 Reinforcement Learning Algorithms 
5.5 Feature Selection Strategies 
5.5.1 Importance of Feature Selection in Malware Detection 
5.5.2 Techniques for Feature Selection 
5.5.3 Optimization for Deep Reinforcement Learning Models 
5.6 Datasets and Evaluation 
5.7 Generating Adversarial Samples 
Conclusion and Future Directions 
Future Directions 
References
6. Artificial Intelligence in Blockchain and Smart Contracts for Disruptive
InnovationEashwar Sivakumar, Kiran Jot Singh and Paras Chawla
6.1 Introduction 
6.1.1 Smart Contract 
6.2 Literature Review 
6.2.1 Blockchain and Smart Contracts in Digital Identity 
6.2.2 Blockchain and Smart Contracts in Financial Security 
6.2.3 Blockchain and Smart Contracts in Supply Chain Management 
6.2.4 Blockchain and Smart Contracts in Insurance 
6.2.5 Blockchain and Smart Contracts in Healthcare 
6.2.6 Blockchain and Smart Contracts in Agriculture 
6.2.7 Blockchain and Smart Contracts in Real Estate 
6.2.8 Blockchain and Smart Contracts in Education and Research 
6.2.9 Blockchain and Smart Contracts in Other Sectors 
6.3 Critical Analysis of the Review 
6.4 Blockchain and Artificial Intelligence 
6.5 Discussion on the Reasoning for Implementation of Blockchain 
6.6 Conclusion 
References 
7. Clinical Intelligence: Deep Reinforcement Learning for Healthcare and Biomedical AdvancementsKeerthika K., Kannan M. and T. Saravanan
7.1 Introduction 
7.2 Deep Reinforcement Learning Methods 
7.2.1 Model-Free Methods 
7.2.2 Policy Gradient Methods 
7.2.3 Model-Based Methods 
7.3 Applications of DRL in Healthcare 
7.3.1 Tailored Treatment Recommendations 
7.3.2 Optimization of Clinical Trials 
7.3.3 Disease Diagnosis Support 
7.3.4 Accelerated Drug Discovery and Design 
7.3.5 Enhanced Robotic Surgery and Assistance 
7.3.6 Health Management System 
7.4 Challenges 
7.5 Healthcare Data Types 
7.5.1 Electronic Healthcare Records (EHRs) 
7.5.2 Laboratory Data 
7.5.3 Sensor Data 
7.5.4 Biomedical Imaging Information 
7.6 Guidelines for the Application of DRL 
7.7 A Case Study: DRL in Healthcare and Biomedical Applications 
7.7.1 Optimizing Radiation Therapy Dose Distribution in Cancer Treatment 
7.7.2 Dose Strategy Model in Sepsis Patient Treatment 
References 
8. Cultivating Expertise in Deep and Reinforcement Learning PrinciplesChilakalapudi Malathi and J. Sheela
8.1 Introduction 
8.1.1 Reinforcement Learning’s Constituent Parts 
8.1.2 Process of Markov Decisions (MDP) 
8.1.3 Learning Reinforcement Methods 
8.2 Intensive Learning Foundations 
8.2.1 A Definition of Deep Learning 
8.2.2 Deep Learning Elements 
8.2.2.1 Different Kinds of Deep Learning Networks 
8.3 Integrating Deep Learning and Reinforcement Learning 
8.3.1 Deep Reinforcement Learning 
8.3.2 Deep Reinforcement Learning Complexity Problems 
Conclusion 
References 
9. Deep Reinforcement Learning in Healthcare and Biomedical ResearchShruti Agrawal and Pralay Mitra
9.1 Introduction 
9.1.1 Reinforcement Learning 
9.1.2 Deep Reinforcement Learning 
9.2 Learning Methods in Bioinformatics with Applications in Healthcare and Biomedical Research 
9.2.1 Protein Folding 
9.2.2 Protein Docking 
9.2.3 Protein–Ligand Binding 
9.2.4 Binding Peptide Generation 
9.2.5 Protein Design and Engineering 
9.2.6 Drug Discovery and Development 
9.3 Applications in Biological Data 
9.3.1 Omics Data 
9.3.2 Medical Imaging 
9.3.3 Brain/Body–Machine Interfaces 
9.4 Adaptive Treatment Approach in Healthcare 
9.5 Diagnostic Tools in Healthcare and Biomedical Research 
9.6 Scope of Deep Reinforcement Learning in Healthcare and Biomedical Applications 
9.6.1 State and Action Space 
9.6.2 Reward 
9.6.3 Policy 
9.6.4 Model Training
9.6.5 Exploration 
9.6.6 Credit Assignment 
9.7 Conclusions 
References 
10. Deep Reinforcement Learning in Robotics and Autonomous SystemsUma Yadav, Shweta V. Bondre and Bhakti Thakre
10.1 Introduction 
10.2 The Promise of Deep Reinforcement Learning (DRL) in Real-World Robotics 
10.3 Preliminaries 
10.4 Enhancing RL for Real-World Robotics 
10.5 Reinforcement Learning for Various Robotic Applications 
10.6 Problems Faced in RL for Robotics 
10.7 RL in Robotics: Trends and Challenges 
10.8 Conclusion 
References
11. Diabetic Retinopathy Detection and Classification Using Deep Reinforcement LearningH.R. Manjunatha and P. Sathish
11.1 Introduction 
11.2 Literature Survey 
11.3 Diabetic Retinopathy Detection and Classification 
11.4 Result Analysis 
11.5 Conclusion 
References 
12. Early Brain Stroke Detection Based on Optimized Cuckoo Search Using LSTM‑Gated Multi-Perceptron Neural NetworkAnita Venaik, Asha A., Dhiyanesh B., Kiruthiga G., Shakkeera L. and Vinodkumar Jacob
12.1 Introduction 
12.2 Literature Survey 
12.2.1 Problem Statement 
12.3 Proposed Methodology 
12.3.1 Dataset Collection 
12.3.2 Preprocessing 
12.3.3 Genetic Feature Sequence Algorithm (GFSA) 
12.3.4 Disease-Prone Factor (DPF) 
12.3.5 Decision Tree-Optimized Cuckoo Search (DTOCS) 
12.3.6 Long Short-Term Memory Gate Multilayer Perceptron Neural Network (LSTM-MLPNN) 
12.4 Result and Discussion 
12.4.1 Performance Matrix 
12.5 Conclusion 
References 
13. Hybrid Approaches: Combining Deep Reinforcement Learning with Other TechniquesM. T. Vasumathi, Manju Sadasivan and Aurangjeb Khan
13.1 Introduction 
13.1.1 Digital Twin—Introduction 
13.1.2 Model of a Digital Twin 
13.1.2.1 Steps Involved in Building a Digital Twin Prototype 
13.1.3 Application Areas of Digital Twins 
13.1.3.1 Digital Twin in Medical Field 
13.1.3.2 Digital Twin in Smart City 
13.1.3.3 Digital Twin in Sports 
13.1.3.4 Digital Twin in Smart Manufacturing 
13.2 Digital Twin Technologies 
13.2.1 Data Acquisition and Sensors 
13.2.2 Data Analytics and Machine Learning 
13.2.3 Cloud Computing 
13.2.4 Other Technologies 
13.3 Integration of RL and Digital Twin 
13.3.1 Motivation for Combining Digital Twin and RL 
13.3.2 How RL Enhances Decision-Making Within Digital Twins 
13.4 Challenges of Using RL in Digital Twins 
13.5 Digital Twin Modeling with RL 
13.6 Technology Underlying RL-Based Digital Twins 
13.6.1 Integration of RL with Digital Twins in Four Stages 
13.6.2 Tools and Libraries for Developing RL-Based Digital Twins 
13.6.2.1 Simulation and Digital Twin Platforms 
13.6.2.2 Reinforcement Learning Libraries 
13.6.3 Integration with Existing Systems and IoT Devices for RL Deployment 
13.6.3.1 Data Collection and Sensor Integration 
13.6.3.2 Communication and Data Ingestion 
13.6.3.3 Digital Twin Integration 
13.6.3.4 RL Integration 
13.6.3.5 Control and Actuation 
13.6.3.6 Implementation of Feedback and Learning Process 
13.6.3.7 Dashboard for Alert and Visualization 
13.6.3.8 Ensuring the Security and Authentication 
13.7 Industry-Specific Applications: A Case Study of DT in a Car Manufacturing Unit 
13.7.1 IoT Components Required for Creating Digital Twin for the Manufacturing Unit 
13.7.2 Architecture of the Proposed Digital Twin for Car Manufacturing Unit 
13.7.3 Challenges and Opportunities in the Implementation of DTs for Car Manufacturing 
13.8 Conclusion 
References 
14. Predictive Modeling of Rheumatoid Arthritis Symptoms: A High-Performance Approach Using HSFO-SVM and UNET-CNNAnusuya V., Baseera A., Dhiyanesh B., Parveen Begam Abdul Kareem and Shanmugaraja P.
14.1 Introduction 
14.1.1 Novelty of the Research 
14.2 Related Work 
14.2.1 Challenges and Problem Identification Factor 
14.3 HSFO-SVM Based on LSTM-Gated Convolution Neural Network (LSTMG-CNN) 
14.3.1 C-Score and Cross-Fold Validation 
14.3.2 Honey Scout Forager Optimization 
14.3.3 Feature Selection Using SVM 
14.3.4 UNET-CNN Classification 
14.4 Result and Discussion 
14.5 Conclusion 
References 
15. Using Reinforcement Learning in Unity Environments for Training AI AgentGeetika Munjal and Monika Lamba
15.1 Introduction 
15.2 Literature Review 
15.3 Machine Learning 
15.3.1 Categorization of Machine Learning 
15.3.1.1 Supervised Learning 
15.3.1.2 Unsupervised Learning 
15.3.1.3 Reinforcement Learning 
15.3.2 Classifying on the Basis of Envisioned Output 
15.3.2.1 Classification 
15.3.2.2 Regression 
15.3.2.3 Clustering 
15.3.3 Artificial Intelligence 
15.4 Unity 
15.4.1 Unity Hub 
15.4.2 Unity Editor 
15.4.3 Inspector 
15.4.4 Game View 
15.4.5 Scene View 
15.4.6 Hierarchy 
15.4.7 Project Window 
15.5 Reinforcement Learning and Supervised Learning 
15.5.1 Positive Reinforcement 
15.5.2 Negative Reinforcement 
15.5.3 Model-Free and Model-Based RL 
15.6 Proposed Model 
15.6.1 Setting Up a Virtual Environment 
15.6.2 Setting Up of the Environment 
15.6.2.1 Creating and Allocating Scripts for the Environment 
15.6.2.2 Creating a Goal for the Agent 
15.6.2.3 Reward-Driven Behavior 
15.7 Markov Decision Process 
15.8 Model-Based RL 
15.9 Experimental Results 
15.9.1 Machine Learning Models Used for the Environments 
15.9.2 PushBlock 
15.9.3 Hallway 
15.9.4 Screenshots of the PushBlock Environment 
15.9.5 Screenshots of the Hallway Environment 
15.10 Conclusion 
References
16. Emerging Technologies in Healthcare SystemsRavi Kumar Sachdeva, Priyanka Bathla, Samriti Vij, Dishika, Madhur Jain, Lokesh Kumar, G. S. Pradeep Ghantasala and Rakesh Ahuja
16.1 Introduction 
16.2 Personalized Medicine 
16.3 AI and ML in Healthcare Sector 
16.3.1 AI in Medical Diagnosis 
16.3.2 Drug Discovery 
16.3.3 Personalized Treatment Plans 
16.3.4 Pattern Matching or Trend Detection 
16.4 Immunotherapy 
16.4.1 Monoclonal Antibodies 
16.4.2 Checkpoint Inhibitors 
16.4.3 CAR-T Cell Therapy 
16.5 Regenerative Medicine 
16.6 Digital Health (Use of Technology in Healthcare) 
16.6.1 Wearable Devices 
16.6.2 Telemedicine 
16.6.3 Electronic Health Records 
16.7 Health Inequity 
16.7.1 Health Disparity 
16.7.2 Health Equity 
16.8 Future Directions in Healthcare Research 
16.9 Challenges and Recommendations for Advanced Level of Modern Healthcare Technologies 
16.9.1 Challenges 
16.9.2 Recommendations 
16.10 Healthcare Sector in Developing and Underdeveloped Countries 
16.10.1 Healthcare Sector in Developing Countries 
16.10.2 Healthcare Sector in Underdeveloped Countries 
16.11 Comparison of Recent Progress and Future Mentoring in Healthcare Using Technology 
16.12 Conclusion 
References 
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